What is the most important information I should know about calcium gluconate? â€¢ Do not take calcium gluconate or antacids containing calcium without first talking to your doctor if you take other medications. Calcium can decrease the effects of many other medicines by binding to them or by changing the acidity of the stomach or the urine. â€¢ Take calcium with meals to increase its absorption by the body. What is calcium gluconate? â€¢ Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body. â€¢ Calcium gluconate is used to prevent and to treat calcium deficiencies. â€¢ Calcium gluconate may also be used for purposes other than those listed in this medication guide. Before taking this medication, tell your doctor if you Â· have had kidney stones; Â· have parathyroid gland disease; Â· take antacids or other calcium supplements; or Â· take a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others). â€¢ You may not be able to take calcium gluconate, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions, or take any of the medications, listed above. â€¢ Talk to your doctor before taking calcium gluconate if you are pregnant. In general, calcium is important for the development of an unborn baby. â€¢ Talk to your doctor before taking calcium gluconate if you are breast-feeding. Calcium is important for the development of a breast-feeding baby.