Epigallocatechin gallate possess the most potent antioxidant activity of the catechins. Epigallocatechin gallate may provide health effects by protecting our cells from oxidative damage from free radicals. A number of chronic disease have been associated with free radical damage, including cancer, arteriosclerosis, heart diseases and accelerated aging. Epigallocatechin gallate interferes with many enzyme systems: it inhibits fast-binding and reversible fatty acid synthase, increases tyrosine phosphorylation of the insulin receptor, activation of ornithine decarboxylase. Epigallocatechin gallate can protect the DNA in the human cells from ultraviolet and visible radiation-induced damage. Epigallocatechin gallate may be effective in promoting fat oxidation and lowering body weight.