Disodium Uridine 5' Monophosphate
DNA (deoxyribonucleic acid), which makes up genetic material, is comprised of units called nucleotides. A nucleotide consists of a base, a sugar and a phosphate group. The major bases in DNA are the purines adenine and guanine and the pyrimidines cytosine and thymine. In the case of RNA, the major bases are again the purines adenine and guanine, and the pyrimidines are cytosine and uracil (Uridine). For years, nucleic acids and nucleotides were not considered essential nutrients. It was thought that the body can synthesize sufficient nucleotides to meet its physiological demands via de novo nucleotide synthetic pathways. Some research during the last several years indicates that this may not be completely correct. There are certain conditions in which the body requires dietary nucleic acids/nucleotides to meet its physiological requirements. These conditions include rapid growth, limited food supply and metabolic stress. There are a few medical foods and enteral supplements containing RNA and nucleotides, which are used for immune-enhancement under conditions of metabolic stress. RNA and nucleotides are sometimes referred to as immunonutrients. Nutritional supplements of RNA, DNA and nucleotides,are also being marketed.