ingredient information
Cobalt in small amounts is essential to many living organisms, including humans. Having 0.13 to 0.30 mg/kg of cobalt in soils markedly improves the health of grazing animals. Cobalt is a central component of the vitamin cobalamin, or vitamin B12. Although cobalt proteins are less common than proteins containing metals like manganese, iron, or zinc, several are known. Most cobalt proteins use a cofactor based on the corrin cobalt, derived from vitamin B12, but there are also a few proteins known in which cobalt is directly coordinated by the protein structure; Methionine aminopeptidase 2 and Nitrile hydratase are two examples Although cobalt is an essential element for life in minute amounts, at higher levels of exposure it shows mutagenic and carcinogenic effects similar to nickel (see Cobalt Poisoning).[29] In 1966, the addition of cobalt compounds to stabilize beer foam in Canada led to cardiomyopathy, which came to be known as beer drinker's cardiomyopathy.[30] Powdered cobalt in metal form is a fire hazard. After nickel and chromium, cobalt is a major cause of contact dermatitis