Chromium is required for normal protein, fat, and carbohydrate metabolism. Chromium plays a role in regulating appetite, reducing the cravings for sugar and increasing lean body mass. Chromium contains a special bioactive formulation called Glucose Tolerance Factor (GTF). GTF facilitates insulin action by binding insulin to cell membranes, serving as a bridge between the insulin molecule and the cell membrane receptor sites. Remember, glucose is used by cells for energy, insulin is used by by the body to transport the glucose into the cells, Chromium's GTF factor essentially assist the glucose to enter the cell. Therefore, all both insulin and GTF are needed for proper glucose metabolism. Chromium deficiency can lead to Type II diabetes and heart disease. Chromium deficiency is thought to contribute to glucose intolerance. Chromium has also been shown to reduce levels of harmful LDL cholesterol (a form of cholesterol that has been linked to heart disease) and increase beneficial HDL cholesterol (HDL cholesterol helps return cholesterol to the liver, keeping it from building up in the blood vessels).