ingredient information
Cetirizine HCI 10 mg
Cetirizine ( /s?'t?r?zi?n/), a third-generation[1] antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. Contents [hide] 1 Availability 2 Pharmacology 3 Administration method and metabolism 4 Indications 4.1 Allergies 4.2 Rhinovirus infection 4.3 Kimura's disease 5 Side Effects 6 Synthesis 7 References 7.1 Books and journals 8 External links [edit] Availability Formerly prescription-only in the USA and Canada, cetirizine is now available over-the-counter in both countries as Zyrtec and Reactine respectively. Zyrtec was the highest-grossing new non-food product of 2008 in the US, generating sales of $315.9 million.[2] It is also available as a generic drug. In Australia and New Zealand, Zyrtec is available over-the-counter in pharmacies and in the UK cetirizine can be sold in limited quantities off-the-shelf in any outlet and is often available in supermarkets. As of 2009, Germany made many generic drugs containing cetirizine available in pharmacies without prescription.[3] Norway, Sweden[4], Finland, and Israel also recognize Cetirizine as an over-the-counter medicine. In India it is sold over-the-counter as brand-name 'Cetzine', even though it remains classified as a Schedule H (prescription) drug[5]